S35R (p.Ser35Arg) variant of SYK (Tyrosine-protein kinase SYK)
S35R (p.Ser35Arg) in SYK (Tyrosine-protein kinase SYK) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.23 / 1. The record also includes population frequency data and structural context.
S35R (p.Ser35Arg) variant details
- p.Ser35Arg
- Ensembl rs2118630296
- Missense
- Variant Prioritization Score for Impact Estimate 0.234
- REVEL 0.37
- CADD 0.13
- PolyPhen-2 0.29
- SIFT 0.08
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available