S35N (p.Ser35Asn) variant of SYK (Tyrosine-protein kinase SYK)
S35N (p.Ser35Asn) in SYK (Tyrosine-protein kinase SYK) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.17 / 1. The record also includes population frequency data and structural context.
S35N (p.Ser35Asn) variant details
- p.Ser35Asn
- TOPMed rs1277403436
- Missense
- Variant Prioritization Score for Impact Estimate 0.166
- REVEL 0.08
- CADD 14.80
- PolyPhen-2 0.02
- SIFT 0.14
- Most common in the South Asian population (allele frequency 5.8e-05)
- Structural context available