P14T (p.Pro14Thr) variant of SYK (Tyrosine-protein kinase SYK)
P14T (p.Pro14Thr) in SYK (Tyrosine-protein kinase SYK) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data, published literature, and structural context.
P14T (p.Pro14Thr) variant details
- p.Pro14Thr
- gnomAD 9-90843938-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.312
- REVEL 0.13
- CADD 22.60
- PolyPhen-2 0.01
- SIFT 0.04
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available
- Literature evidence available