N46S (p.Asn46Ser) variant of SYK (Tyrosine-protein kinase SYK)
N46S (p.Asn46Ser) in SYK (Tyrosine-protein kinase SYK) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data and structural context.
N46S (p.Asn46Ser) variant details
- p.Asn46Ser
- gnomAD rs1205743055
- Missense
- Variant Prioritization Score for Impact Estimate 0.186
- REVEL 0.05
- CADD 17.90
- PolyPhen-2 0.08
- SIFT 0.28
- Most common in the REMAINING population (allele frequency 0.00048)
- Structural context available