N19S (p.Asn19Ser) variant of SYK (Tyrosine-protein kinase SYK)
N19S (p.Asn19Ser) in SYK (Tyrosine-protein kinase SYK) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.43 / 1. The record also includes population frequency data and structural context.
N19S (p.Asn19Ser) variant details
- p.Asn19Ser
- ExAC rs745568763
- TOPMed rs745568763
- gnomAD rs745568763
- Missense
- Variant Prioritization Score for Impact Estimate 0.435
- REVEL 0.33
- CADD 19.30
- PolyPhen-2 0.30
- SIFT 1.00
- Most common in the African/African-American population (allele frequency 7.2e-05)
- Structural context available