N11K (p.Asn11Lys) variant of SYK (Tyrosine-protein kinase SYK)
N11K (p.Asn11Lys) in SYK (Tyrosine-protein kinase SYK) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.15 / 1. The record also includes population frequency data, published literature, and structural context.
N11K (p.Asn11Lys) variant details
- p.Asn11Lys
- gnomAD 9-90843931-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.155
- REVEL 0.06
- CADD 14.70
- PolyPhen-2 0.08
- SIFT 0.83
- Most common in the Non-Finnish European population (allele frequency 9.2e-07)
- Structural context available
- Literature evidence available