M6T (p.Met6Thr) variant of SYK (Tyrosine-protein kinase SYK)
M6T (p.Met6Thr) in SYK (Tyrosine-protein kinase SYK) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data and structural context.
M6T (p.Met6Thr) variant details
- p.Met6Thr
- ExAC rs201350143
- TOPMed rs201350143
- gnomAD rs201350143
- Missense
- Variant Prioritization Score for Impact Estimate 0.194
- REVEL 0.17
- CADD 12.10
- PolyPhen-2 0.00
- SIFT 0.04
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available