L38F (p.Leu38Phe) variant of SYK (Tyrosine-protein kinase SYK)
L38F (p.Leu38Phe) in SYK (Tyrosine-protein kinase SYK) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.68 / 1. The record also includes population frequency data and structural context.
L38F (p.Leu38Phe) variant details
- p.Leu38Phe
- Ensembl rs2118630553
- Missense
- Variant Prioritization Score for Impact Estimate 0.682
- REVEL 0.69
- CADD 24.50
- PolyPhen-2 0.97
- SIFT 0.01
- Most common in the South Asian population (allele frequency 2.3e-05)
- Structural context available