L29M (p.Leu29Met) variant of SYK (Tyrosine-protein kinase SYK)
L29M (p.Leu29Met) in SYK (Tyrosine-protein kinase SYK) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.41 / 1. The record also includes population frequency data and structural context.
L29M (p.Leu29Met) variant details
- p.Leu29Met
- TOPMed rs1276343036
- gnomAD rs1276343036
- Missense
- Variant Prioritization Score for Impact Estimate 0.411
- REVEL 0.43
- CADD 24.20
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available