L13M (p.Leu13Met) variant of SYK (Tyrosine-protein kinase SYK)
L13M (p.Leu13Met) in SYK (Tyrosine-protein kinase SYK) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data, published literature, and structural context.
L13M (p.Leu13Met) variant details
- p.Leu13Met
- gnomAD 9-90843935-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.344
- REVEL 0.26
- CADD 22.50
- PolyPhen-2 1.00
- SIFT 0.09
- Population evidence available
- Structural context available
- Literature evidence available