G5R (p.Gly5Arg) variant of SYK (Tyrosine-protein kinase SYK)
G5R (p.Gly5Arg) in SYK (Tyrosine-protein kinase SYK) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data and structural context.
G5R (p.Gly5Arg) variant details
- p.Gly5Arg
- ESP rs146743944
- ExAC rs146743944
- TOPMed rs146743944
- gnomAD rs146743944
- Missense
- Variant Prioritization Score for Impact Estimate 0.339
- REVEL 0.19
- CADD 1.01
- PolyPhen-2 0.03
- SIFT 0.54
- Most common in the Non-Finnish European population (allele frequency 9.3e-07)
- Structural context available