G5D (p.Gly5Asp) variant of SYK (Tyrosine-protein kinase SYK)
G5D (p.Gly5Asp) in SYK (Tyrosine-protein kinase SYK) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.28 / 1. The record also includes population frequency data and structural context.
G5D (p.Gly5Asp) variant details
- p.Gly5Asp
- 1000Genomes rs2118628028
- Missense
- Variant Prioritization Score for Impact Estimate 0.279
- REVEL 0.18
- CADD 6.16
- PolyPhen-2 0.01
- SIFT 0.62
- Most common in the Non-Finnish European population (allele frequency 4.7e-06)
- Structural context available