G33V (p.Gly33Val) variant of SYK (Tyrosine-protein kinase SYK)
G33V (p.Gly33Val) in SYK (Tyrosine-protein kinase SYK) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.64 / 1. The record also includes population frequency data, published literature, and structural context.
G33V (p.Gly33Val) variant details
- p.Gly33Val
- gnomAD 9-90843996-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.638
- REVEL 0.60
- CADD 27.30
- PolyPhen-2 0.99
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available