G33A (p.Gly33Ala) variant of SYK (Tyrosine-protein kinase SYK)
G33A (p.Gly33Ala) in SYK (Tyrosine-protein kinase SYK) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.43 / 1. The record also includes population frequency data and structural context.
G33A (p.Gly33Ala) variant details
- p.Gly33Ala
- ExAC rs766412303
- TOPMed rs766412303
- gnomAD rs766412303
- Missense
- Variant Prioritization Score for Impact Estimate 0.429
- REVEL 0.24
- CADD 26.30
- PolyPhen-2 0.89
- SIFT 0.02
- Most common in the Latino/Admixed American population (allele frequency 2.3e-05)
- Structural context available