G18S (p.Gly18Ser) variant of SYK (Tyrosine-protein kinase SYK)
G18S (p.Gly18Ser) in SYK (Tyrosine-protein kinase SYK) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.66 / 1. The record also includes population frequency data and structural context.
G18S (p.Gly18Ser) variant details
- p.Gly18Ser
- ExAC rs752280694
- gnomAD rs752280694
- Missense
- Variant Prioritization Score for Impact Estimate 0.655
- REVEL 0.51
- CADD 32.00
- PolyPhen-2 1.00
- SIFT 0.04
- Most common in the Finnish in Finland (FIN) population (allele frequency 9.6e-05)
- Structural context available