G18D (p.Gly18Asp) variant of SYK (Tyrosine-protein kinase SYK)
G18D (p.Gly18Asp) in SYK (Tyrosine-protein kinase SYK) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.73 / 1. The record also includes population frequency data and structural context.
G18D (p.Gly18Asp) variant details
- p.Gly18Asp
- cosmic curated COSV65328
- Ensembl rs2118628863
- Missense
- Variant Prioritization Score for Impact Estimate 0.734
- REVEL 0.69
- CADD 27.70
- PolyPhen-2 1.00
- SIFT 0.00
- Population evidence available
- Structural context available