E23K (p.Glu23Lys) variant of SYK (Tyrosine-protein kinase SYK)
E23K (p.Glu23Lys) in SYK (Tyrosine-protein kinase SYK) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.71 / 1. The record also includes population frequency data and structural context.
E23K (p.Glu23Lys) variant details
- p.Glu23Lys
- Ensembl rs2118629309
- Missense
- Variant Prioritization Score for Impact Estimate 0.707
- REVEL 0.66
- CADD 25.00
- PolyPhen-2 1.00
- SIFT 0.14
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available