A7V (p.Ala7Val) variant of SYK (Tyrosine-protein kinase SYK)
A7V (p.Ala7Val) in SYK (Tyrosine-protein kinase SYK) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.18 / 1. The record also includes population frequency data and structural context.
A7V (p.Ala7Val) variant details
- p.Ala7Val
- ExAC rs756007618
- TOPMed rs756007618
- gnomAD rs756007618
- Missense
- Variant Prioritization Score for Impact Estimate 0.176
- REVEL 0.06
- CADD 14.10
- PolyPhen-2 0.00
- SIFT 0.17
- Most common in the REMAINING population (allele frequency 0.00048)
- Structural context available