A7T (p.Ala7Thr) variant of SYK (Tyrosine-protein kinase SYK)
A7T (p.Ala7Thr) in SYK (Tyrosine-protein kinase SYK) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data and structural context.
A7T (p.Ala7Thr) variant details
- p.Ala7Thr
- ExAC rs752678021
- Missense
- Variant Prioritization Score for Impact Estimate 0.22
- REVEL 0.10
- CADD 10.90
- PolyPhen-2 0.12
- SIFT 0.59
- Most common in the Middle Eastern population (allele frequency 0.00018)
- Structural context available