A7G (p.Ala7Gly) variant of SYK (Tyrosine-protein kinase SYK)
A7G (p.Ala7Gly) in SYK (Tyrosine-protein kinase SYK) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.21 / 1. The record also includes population frequency data and structural context.
A7G (p.Ala7Gly) variant details
- p.Ala7Gly
- ExAC rs756007618
- TOPMed rs756007618
- gnomAD rs756007618
- Missense
- Variant Prioritization Score for Impact Estimate 0.214
- REVEL 0.13
- CADD 14.10
- PolyPhen-2 0.00
- SIFT 0.15
- Most common in the Latino/Admixed American population (allele frequency 5.3e-05)
- Structural context available