A10T (p.Ala10Thr) variant of SYK (Tyrosine-protein kinase SYK)
A10T (p.Ala10Thr) in SYK (Tyrosine-protein kinase SYK) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.51 / 1. The record also includes population frequency data and structural context.
A10T (p.Ala10Thr) variant details
- p.Ala10Thr
- ExAC rs199606629
- TOPMed rs199606629
- gnomAD rs199606629
- Missense
- Variant Prioritization Score for Impact Estimate 0.512
- REVEL 0.35
- CADD 26.40
- PolyPhen-2 0.48
- SIFT 0.01
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available