A10S (p.Ala10Ser) variant of SYK (Tyrosine-protein kinase SYK)
A10S (p.Ala10Ser) in SYK (Tyrosine-protein kinase SYK) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.49 / 1. The record also includes population frequency data and structural context.
A10S (p.Ala10Ser) variant details
- p.Ala10Ser
- ExAC rs199606629
- TOPMed rs199606629
- gnomAD rs199606629
- Missense
- Variant Prioritization Score for Impact Estimate 0.494
- REVEL 0.32
- CADD 24.20
- PolyPhen-2 0.80
- SIFT 0.13
- Population evidence available
- Structural context available