A10P (p.Ala10Pro) variant of SYK (Tyrosine-protein kinase SYK)
A10P (p.Ala10Pro) in SYK (Tyrosine-protein kinase SYK) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.57 / 1. The record also includes population frequency data and structural context.
A10P (p.Ala10Pro) variant details
- p.Ala10Pro
- ExAC rs199606629
- TOPMed rs199606629
- gnomAD rs199606629
- Missense
- Variant Prioritization Score for Impact Estimate 0.573
- REVEL 0.43
- CADD 28.20
- PolyPhen-2 0.99
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 2.8e-06)
- Structural context available