P61A (p.Pro61Ala) variant of SV2A (Synaptic vesicle glycoprotein 2A)
P61A (p.Pro61Ala) in SV2A (Synaptic vesicle glycoprotein 2A) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.18 / 1. The record also includes population frequency data and structural context.
P61A (p.Pro61Ala) variant details
- p.Pro61Ala
- ExAC rs782533416
- gnomAD rs782533416
- Missense
- Variant Prioritization Score for Impact Estimate 0.184
- REVEL 0.02
- ESM-1b 0.00
- AlphaMissense 0.05
- MetaLR 0.04
- MetaSVM -1.09
- CADD 16.90
- Most common in the Finnish in Finland (FIN) population (allele frequency 9.7e-05)
- Structural context available