T35M (p.Thr35Met) variant of SUZ12 (Polycomb protein SUZ12)
T35M (p.Thr35Met) in SUZ12 (Polycomb protein SUZ12) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.42 / 1. The record also includes population frequency data and structural context.
T35M (p.Thr35Met) variant details
- p.Thr35Met
- gnomAD rs1285528720
- Missense
- Variant Prioritization Score for Impact Estimate 0.416
- REVEL 0.32
- MetaLR 0.39
- MetaSVM -0.53
- CADD 20.60
- PolyPhen-2 0.00
- SIFT 0.18
- Most common in the Non-Finnish European population (allele frequency 1.9e-06)
- Structural context available