T35A (p.Thr35Ala) variant of SUZ12 (Polycomb protein SUZ12)
T35A (p.Thr35Ala) in SUZ12 (Polycomb protein SUZ12) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.18 / 1. The record also includes population frequency data and structural context.
T35A (p.Thr35Ala) variant details
- p.Thr35Ala
- TOPMed rs1224696424
- gnomAD rs1224696424
- Missense
- Variant Prioritization Score for Impact Estimate 0.18
- REVEL 0.12
- MetaLR 0.32
- MetaSVM -0.79
- CADD 16.20
- PolyPhen-2 0.01
- SIFT 0.81
- Most common in the East Asian population (allele frequency 6.8e-05)
- Structural context available