S41P (p.Ser41Pro) variant of SUZ12 (Polycomb protein SUZ12)
S41P (p.Ser41Pro) in SUZ12 (Polycomb protein SUZ12) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data, published literature, and structural context.
S41P (p.Ser41Pro) variant details
- p.Ser41Pro
- gnomAD 17-31937367-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.294
- REVEL 0.24
- MetaLR 0.32
- MetaSVM -0.64
- CADD 22.70
- PolyPhen-2 0.04
- SIFT 0.36
- Most common in the Non-Finnish European population (allele frequency 9.4e-07)
- Structural context available
- Literature evidence available