P16R (p.Pro16Arg) variant of SUZ12 (Polycomb protein SUZ12)
P16R (p.Pro16Arg) in SUZ12 (Polycomb protein SUZ12) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.45 / 1. The record also includes population frequency data and structural context.
P16R (p.Pro16Arg) variant details
- p.Pro16Arg
- ExAC rs765010301
- TOPMed rs765010301
- gnomAD rs765010301
- Missense
- Variant Prioritization Score for Impact Estimate 0.448
- REVEL 0.27
- MetaLR 0.35
- MetaSVM -0.66
- CADD 23.60
- SIFT 0.23
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available