G39S (p.Gly39Ser) variant of SUZ12 (Polycomb protein SUZ12)
G39S (p.Gly39Ser) in SUZ12 (Polycomb protein SUZ12) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.37 / 1. The record also includes population frequency data and structural context.
G39S (p.Gly39Ser) variant details
- p.Gly39Ser
- cosmic curated COSV10589
- TOPMed rs1001318910
- gnomAD rs1001318910
- Missense
- Variant Prioritization Score for Impact Estimate 0.369
- REVEL 0.20
- MetaLR 0.45
- MetaSVM -0.43
- CADD 22.60
- PolyPhen-2 0.00
- SIFT 0.22
- Most common in the Non-Finnish European population (allele frequency 0.00051)
- Structural context available