G26W (p.Gly26Trp) variant of SUZ12 (Polycomb protein SUZ12)
G26W (p.Gly26Trp) in SUZ12 (Polycomb protein SUZ12) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.59 / 1. The record also includes population frequency data and structural context.
G26W (p.Gly26Trp) variant details
- p.Gly26Trp
- TOPMed rs1421240953
- gnomAD rs1421240953
- Missense
- Variant Prioritization Score for Impact Estimate 0.591
- REVEL 0.48
- MetaLR 0.68
- MetaSVM 0.53
- CADD 31.00
- PolyPhen-2 0.99
- SIFT 0.17
- Most common in the Non-Finnish European population (allele frequency 2.9e-06)
- Structural context available