G26E (p.Gly26Glu) variant of SUZ12 (Polycomb protein SUZ12)
G26E (p.Gly26Glu) in SUZ12 (Polycomb protein SUZ12) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.54 / 1. The record also includes population frequency data, published literature, and structural context.
G26E (p.Gly26Glu) variant details
- p.Gly26Glu
- gnomAD 17-31937323-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.545
- REVEL 0.42
- MetaLR 0.55
- MetaSVM 0.18
- CADD 24.40
- PolyPhen-2 0.45
- SIFT 0.26
- Most common in the African/African-American population (allele frequency 3.8e-05)
- Structural context available
- Literature evidence available