G21W (p.Gly21Trp) variant of SUZ12 (Polycomb protein SUZ12)
G21W (p.Gly21Trp) in SUZ12 (Polycomb protein SUZ12) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.51 / 1. The record also includes population frequency data, published literature, and structural context.
G21W (p.Gly21Trp) variant details
- p.Gly21Trp
- gnomAD 17-31937307-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.515
- REVEL 0.48
- MetaLR 0.46
- MetaSVM 0.01
- CADD 29.00
- PolyPhen-2 0.89
- SIFT 0.07
- Population evidence available
- Structural context available
- Literature evidence available