G21R (p.Gly21Arg) variant of SUZ12 (Polycomb protein SUZ12)
G21R (p.Gly21Arg) in SUZ12 (Polycomb protein SUZ12) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.39 / 1. The record also includes population frequency data, published literature, and structural context.
G21R (p.Gly21Arg) variant details
- p.Gly21Arg
- gnomAD 17-31937307-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.392
- REVEL 0.30
- MetaLR 0.30
- MetaSVM -0.49
- CADD 24.10
- PolyPhen-2 0.01
- SIFT 0.14
- Most common in the Non-Finnish European population (allele frequency 1.9e-06)
- Structural context available
- Literature evidence available