G19W (p.Gly19Trp) variant of SUZ12 (Polycomb protein SUZ12)
G19W (p.Gly19Trp) in SUZ12 (Polycomb protein SUZ12) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.54 / 1. The record also includes population frequency data and structural context.
G19W (p.Gly19Trp) variant details
- p.Gly19Trp
- Ensembl rs1905989323
- Missense
- Variant Prioritization Score for Impact Estimate 0.539
- REVEL 0.44
- MetaLR 0.51
- MetaSVM -0.02
- CADD 25.30
- PolyPhen-2 0.22
- SIFT 0.07
- Most common in the East Asian population (allele frequency 3.6e-05)
- Structural context available