F25V (p.Phe25Val) variant of SUZ12 (Polycomb protein SUZ12)
F25V (p.Phe25Val) in SUZ12 (Polycomb protein SUZ12) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.37 / 1. The record also includes population frequency data, published literature, and structural context.
F25V (p.Phe25Val) variant details
- p.Phe25Val
- gnomAD 17-31937319-T-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.373
- REVEL 0.30
- MetaLR 0.30
- MetaSVM -0.55
- CADD 23.20
- PolyPhen-2 0.06
- SIFT 0.40
- Most common in the Non-Finnish European population (allele frequency 9.6e-07)
- Structural context available
- Literature evidence available