F25S (p.Phe25Ser) variant of SUZ12 (Polycomb protein SUZ12)
F25S (p.Phe25Ser) in SUZ12 (Polycomb protein SUZ12) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data, published literature, and structural context.
F25S (p.Phe25Ser) variant details
- p.Phe25Ser
- gnomAD 17-31937320-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.274
- REVEL 0.15
- MetaLR 0.28
- MetaSVM -0.68
- CADD 23.20
- PolyPhen-2 0.00
- SIFT 0.28
- Most common in the Non-Finnish European population (allele frequency 1.9e-06)
- Structural context available
- Literature evidence available