A34S (p.Ala34Ser) variant of SUZ12 (Polycomb protein SUZ12)
A34S (p.Ala34Ser) in SUZ12 (Polycomb protein SUZ12) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data and structural context.
A34S (p.Ala34Ser) variant details
- p.Ala34Ser
- TOPMed rs1021200184
- gnomAD rs1021200184
- Missense
- Variant Prioritization Score for Impact Estimate 0.268
- REVEL 0.12
- MetaLR 0.25
- MetaSVM -0.94
- CADD 21.00
- PolyPhen-2 0.01
- SIFT 0.45
- Most common in the African/African-American population (allele frequency 4.8e-05)
- Structural context available