A33S (p.Ala33Ser) variant of SUZ12 (Polycomb protein SUZ12)
A33S (p.Ala33Ser) in SUZ12 (Polycomb protein SUZ12) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.36 / 1. The record also includes population frequency data and structural context.
A33S (p.Ala33Ser) variant details
- p.Ala33Ser
- gnomAD rs1391996815
- Missense
- Variant Prioritization Score for Impact Estimate 0.357
- REVEL 0.15
- MetaLR 0.27
- MetaSVM -0.91
- CADD 22.20
- PolyPhen-2 0.00
- SIFT 0.88
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available