T21N (p.Thr21Asn) variant of SUFU (Suppressor of fused homolog)
T21N (p.Thr21Asn) in SUFU (Suppressor of fused homolog) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data, published literature, and structural context.
T21N (p.Thr21Asn) variant details
- p.Thr21Asn
- gnomAD 10-102504214-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.192
- REVEL 0.08
- CADD 15.50
- PolyPhen-2 0.00
- SIFT 0.50
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available
- Literature evidence available