P16Q (p.Pro16Gln) variant of SUFU (Suppressor of fused homolog)
P16Q (p.Pro16Gln) in SUFU (Suppressor of fused homolog) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.37 / 1. The record also includes population frequency data, published literature, and structural context.
P16Q (p.Pro16Gln) variant details
- p.Pro16Gln
- gnomAD 10-102504199-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.373
- REVEL 0.12
- CADD 22.20
- PolyPhen-2 0.02
- SIFT 0.06
- Most common in the Non-Finnish European population (allele frequency 9.1e-07)
- Structural context available
- Literature evidence available