L4M (p.Leu4Met) variant of SUFU (Suppressor of fused homolog)
L4M (p.Leu4Met) in SUFU (Suppressor of fused homolog) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.28 / 1. The record also includes population frequency data, published literature, and structural context.
L4M (p.Leu4Met) variant details
- p.Leu4Met
- gnomAD 10-102504162-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.282
- REVEL 0.09
- CADD 22.80
- PolyPhen-2 0.00
- SIFT 0.04
- Population evidence available
- Structural context available
- Literature evidence available