A17S (p.Ala17Ser) variant of SUFU (Suppressor of fused homolog)
A17S (p.Ala17Ser) in SUFU (Suppressor of fused homolog) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data and structural context.
A17S (p.Ala17Ser) variant details
- p.Ala17Ser
- NCI-TCGA TCGA novel
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.306
- REVEL 0.08
- CADD 21.70
- PolyPhen-2 0.03
- SIFT 0.38
- UniProt: Variant assessed as somatic; moderate impact.
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available