S19S (p.Ser19Ser) variant of STK11 (Q15831)
S19S (p.Ser19Ser) in STK11 (Q15831) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data, published literature, and structural context.
S19S (p.Ser19Ser) variant details
- p.Ser19Ser
- rs748698151
- gnomAD 19-1206970-G-A
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.267
- AlphaMissense 0.12
- MetaLR 0.54
- MetaSVM -0.04
- CADD 9.10
- PolyPhen-2 0.97
- SIFT 0.03
- Most common in the Non-Finnish European population (allele frequency 9.3e-07)
- Structural context available
- Literature evidence available