L9M (p.Leu9Met) variant of STK11 (Q15831)
L9M (p.Leu9Met) in STK11 (Q15831) is a missense change. Clinical records from EBI and UniProt describe it as likely benign. The available variant effect predictions contribute to a CATVariant prioritization score of 0.20 / 1. The record also includes population frequency data and structural context.
L9M (p.Leu9Met) variant details
- p.Leu9Met
- gnomAD rs876661079
- Likely benign
- Missense
- Variant Prioritization Score for Impact Estimate 0.196
- REVEL 0.08
- MetaLR 0.17
- MetaSVM -0.90
- CADD 20.80
- PolyPhen-2 0.00
- SIFT 0.14
- EBI: Likely benign
- UniProt: Likely benign
- Population evidence available
- Structural context available