E14E (p.Glu14Glu) variant of STK11 (Q15831)
E14E (p.Glu14Glu) in STK11 (Q15831) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data, published literature, and structural context.
E14E (p.Glu14Glu) variant details
- p.Glu14Glu
- rs758769888
- gnomAD 19-1206955-G-A
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.293
- AlphaMissense 0.07
- MetaLR 0.10
- MetaSVM -1.05
- CADD 13.10
- PolyPhen-2 0.00
- SIFT 0.37
- Most common in the South Asian population (allele frequency 0.00044)
- Structural context available
- Literature evidence available