D5D (p.Asp5Asp) variant of STK11 (Q15831)
D5D (p.Asp5Asp) in STK11 (Q15831) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.46 / 1. The record also includes population frequency data, published literature, and structural context.
D5D (p.Asp5Asp) variant details
- p.Asp5Asp
- rs786201498
- gnomAD 19-1206928-C-T
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.455
- AlphaMissense 0.07
- MetaLR 0.09
- MetaSVM -1.05
- CADD 11.70
- PolyPhen-2 0.00
- SIFT 0.06
- Most common in the Ashkenazi Jewish population (allele frequency 5.1e-05)
- Structural context available
- Literature evidence available