D23D (p.Asp23Asp) variant of STK11 (Q15831)
D23D (p.Asp23Asp) in STK11 (Q15831) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.48 / 1. The record also includes population frequency data, published literature, and structural context.
D23D (p.Asp23Asp) variant details
- p.Asp23Asp
- rs1599914867
- gnomAD 19-1206982-C-T
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.478
- AlphaMissense 0.41
- MetaLR 0.52
- MetaSVM -0.22
- CADD 13.90
- PolyPhen-2 0.89
- SIFT 0.02
- Most common in the Non-Finnish European population (allele frequency 3.4e-06)
- Structural context available
- Literature evidence available