S86R (p.Ser86Arg) variant of STAT6 (P42226)
S86R (p.Ser86Arg) in STAT6 (P42226) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.23 / 1. The record also includes population frequency data and structural context.
S86R (p.Ser86Arg) variant details
- p.Ser86Arg
- TOPMed rs2034335639
- Missense
- Variant Prioritization Score for Impact Estimate 0.226
- REVEL 0.08
- CADD 19.80
- PolyPhen-2 0.01
- SIFT 0.25
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available