S86I (p.Ser86Ile) variant of STAT6 (P42226)
S86I (p.Ser86Ile) in STAT6 (P42226) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.17 / 1. The record also includes population frequency data and structural context.
S86I (p.Ser86Ile) variant details
- p.Ser86Ile
- gnomAD rs1232270313
- Missense
- Variant Prioritization Score for Impact Estimate 0.174
- REVEL 0.10
- CADD 19.00
- PolyPhen-2 0.06
- SIFT 0.06
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available