S45T (p.Ser45Thr) variant of STAT6 (P42226)
S45T (p.Ser45Thr) in STAT6 (P42226) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data and structural context.
S45T (p.Ser45Thr) variant details
- p.Ser45Thr
- Ensembl rs2034363993
- Missense
- Variant Prioritization Score for Impact Estimate 0.236
- REVEL 0.13
- CADD 22.70
- PolyPhen-2 0.94
- SIFT 0.03
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available